Explore by gene
From genetic association
to biological meaning.
Gene pages bring together disease associations, relevant variants and the evidence connecting genetic signals to function.
Gene library
Only genes supported by robust genetic evidence are included. Each page distinguishes association from functional interpretation.
Gene
TYK2
Tyrosine kinase 2A signalling kinase linking cytokine receptors to intracellular immune responses.
Associated diseasesLupusPsoriasisRheumatoid arthritis
→Gene
IFIH1
Interferon induced with helicase C domain 1An innate immune sensor involved in recognising viral RNA and activating interferon responses.
Associated diseasesLupusType 1 diabetes
→Gene
IRF5
Interferon regulatory factor 5A transcription factor influencing inflammatory and type I interferon pathways.
Associated diseasesLupusInflammatory bowel disease
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