Lupus genetics
Genes associated with lupus
Gene profiles connect robust SLE association signals to their likely causal variants, biological effects and supporting evidence.
Evidence library
SLE-associated genes
InsideGen distinguishes evidence for association from evidence about causal variants and biological mechanism. More gene profiles will be added as their evidence is reviewed.
Gene profileTwo independent signals
TYK2
Tyrosine kinase 2
Strong, consistently replicated evidence for association with SLE.View TYK2 evidence →Additional reviewed gene profiles will appear here.